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with benzine and disinfected twice with tincture of iodine. A puncture was made in the middle of the suppurating gland very quickly with a narrow scalpel, no anesthesia being employed. The pus was removed with a Bier suction. cup and by gentie pressure along the edges of the bubo. The cavity was then filled with methylene blue silver solution by means of a 10 c.c syringe with an asbestos piston. A moist dressing was then applied and not removed for forty-eight hours. Whether 1⁄2 per cent, 1 per cent, 2 per cent or 5 per cent solutions were used made no apparent difference. The remedy produced absolutely no pain. at the first change of dressing, it was possible to express serum, the injection of methylene blue silver was repeated twice or three times at intervals of two or three days, while the absorption of infiltrations was hastened by the local application of moist heat. Control treatment was carried out chiefly in cases having buboes on both sides. One per cent silver nitrate, 5 or 10 per cent protargol, 1 per cent sodium chloride and sterile water were used. Of these sterile water showed the greatest efficiency, but it could not equal the results occasioned by methylene blue silver. From their investigations the authors conclude that in the treatment of suppurating inguinal adenitis, the best results by far are obtained with methylene blue silver.-Med. Fortnightly.

COLLOIDAL COPPER IN THE CURE OF CANCER:-Among the numerous remedies suggested for the cure of cancer in the cases in which the surgeon finds himself impotent, namely, when the cancer is disseminated with deep nodules and undermining infiltrations, inaccessible and inoperable, attention has been called to substances capable of fixing themselves upon the neoplastic tissues or upon the parasitic agents.

Among the many disappointments caused by the use of such remedies, it seems that results really extraordinary,

so much so because they concern inoperable cases, have been obtained by a chemical preparation of colloidal protoxis hydrate of copper, which the discoverer has named cuprase, and it is used hypodermically. It is put up in ampoules of 5 c.c., each containing 121-100 of a milligram of copper.

Under the action of the remedy, according to the report of several experimenters, the cancerous tumors decrease in volume, and at the same time the infiltrated ganglia become smaller and the pain is lessened and ceases.

Wolze and A. Pagenstecker (Munch. mediz Wochen, 1913, No. 19), report the case of a man sixty-eight years old who had a sarcoma involving the right tonsil and the pharynx, with large ulcerations. The nature of the tumor had been confirmed by histologic examination. In the three last months, owing to the impossiiblity of taking sufficient nourishment, the patient had lost weight to an alarming degree. The various treatments employed, including radio therapy, having failed, the above named doctors decided to try the injections of cuprase in doses of 5 c.c. each, and in seven months they injected 687 hundred milligrams of pure copper. The result was unexpected, because the treatment produced an improvement of the general condition and a reduction of the tumor.

After a certain period of such treatment, the patient was put again under the prophylaxis of the X-rays, and the improvement already obtained by the hypodermic injections of the cuprase became so marked that he gained thirteen kilograms, and was able to return to his occupation.

Considering that the X-rays, already used before the new treatment, had not given satisfactory results, it must be admitted that the greatest benefit was obtained by the injections of cuprase, and the more so considering the good results that many other experimenters claim by the exclusive use of this remedy.-Rivista Medica, Milan, May 20, 1914.

A CASE OF GIANT CELL SARCOMA SUCCESSFULLY TREATED BY A COMBINATION OF SURGERY AND THE X-RAYS:-Cures of sarcoma have been previously reported by Pfahler and others. The report of the following case was withheld until a sufficient length of time had elapsed to warrant any positive claims for the action of the rays.

Case.-J. H., age 55; married, 3 children. No family history of malignancy. Had been in good health until the summer of 1910, when a small mass appeared in the neck on the right side, just below the angle of the jaw. This was diagnosed as an enlarged gland and non-interference was advised.

The mass increased in size so rapidly that both physician and patient became alarmed and it was removed. A microscopical examination proved it to be a giant cell sarcoma.

Within a period of less than four weeks another small mass appeared in the neck and X-ray treatments were advised. The mass measured about two inches in diameter and was freely movable. Two erythema doses, in a series of twelve treatments each, were given. A filter of heavy sole leather was used and an interval of four weeks was allowed between each series.

At the end of the second series the mass was about onehalf inch in diameter. A severe dermatitis then appeared and further treatments were considered inadvisable. The remaining mass was again removed.

Immediately following this operation, the patient contracted a severe attack of erysipelas which kept him in bed for about two months. small mass appeared, and as turned for X-ray treatments. disappeared.

During this period another soon as he was able he reThis time the mass entirely

During the following year the patient returned for observation at intervals of about six weeks. There was no evidence of a recurrence.

It is now three years and a half since the last treatments were given and the patient is apparently in fine health.

The incident of the erysipelas seemed to cloud the issue in the mind of the surgeon and he was inclined to give it the credit for arresting the disease. Inasmuch as recurrence took place during and after the attack of erysipelas and the growth was not checked until after X-ray treatments were again begun, his opinion was, I think, not well founded.-Edgar Birdsall, M.D., in N. Y. Med. Record.

CANCER OF THE BREAST:-Dr. William L. Rodman, of Philadelphia, at the recent meeting of the Southern Medical Association in Richmond, Va., gave an address on this subject, which was illustrated by numerous lantern slides. He stated that the proper treatment for cancer was early removal. Much had been said about the X-ray and radium, neither of which had been of demonstrable worth from the standpoint of permanent cure. He had not in his experience seen a case of cancer cured either by the X-ray or radium permanently. Of those cases reported to have been relieved or cured, the original tumor or growth might have been benign instead of malignant. He believed more in the X-ray than in radium, and what had been accomplished by radium had been done better by the X-ray. He thought the profession was running after false gods when they gave up surgical operation for these new fads. The speaker said that between 12,000 and 15,000 men and women died annually from this deceitfully terrible disease. If the disease were taken in time, when only suspicion was existent, a cure could be effected; but in the majority-and it was a tremendous majority-of cases the patient came. too late, or the diagnosis was made too late, to be cured. A careful study of precancerous conditions should be made and all measures of early diagnosis and precaution should be carried to the ultima thule of safety. Cancer was. strictly local in the beginning, as shown by every evidence, clinical, surgical, and indicative. Part of the evidence that it was primarily a local disease was that it was not painful in the first year or eighteen months. It was

only when adhesions began and secondary ulcerations appeared that the disease was painful. In the beginning it was strictly painless. The patients ate and slept well and went through the ordinary routine of life as if there were nothing the matter with them. If an operation was performed in the early stages, before the disease had become constitutional, a cure would result. If, however, cancer of the breast were allowed to continue until there was an enlargement of the glands under the armpit, only 25.4 per cent of the cases would be cured. The disease became secondary, or constitutional, only by transfer from the primary focus, as when it entered and attacked the lymphatic glands. Until this transfer had occurred Dr. Rodman maintained it was strictly local.-Med. Record, Dec. 19, 1914.

CHANCROID, FUCHSIN IN:-Fuchsin in a 5 per cent ointment with petrolatum has been found of benefit in the treatment of carbuncles, and this led the author to try it in soft chancres. Nine cases of undoubted soft chancre showed so much benefit that he is convinced there is no other drug which is so useful. Under ordinary treatment soft sores take about six weeks to heal up, while with fuchsin he has been able to heal them in less than two weeks. The average duration of treatment was eight days.

One case was complicated with bubo in the left groin as large as a small orange. With fuchsin ointment the chancroid healed in six days, and the bubo, which had threatened to suppurate, at once subsided. The ointment of fuchsin (aniline red) is applied to the chancre, after first washing and then drying it. If the prepuce can be brought over the glans penis no other dressing is required, although it is to be noted that fuchsin stains the linen red. The author requires the patient to clean the parts and apply the ointment twice a day, simply because it is difficult to get poor people to learn the benefits of keeping clean. Otherwise, in his opinion, a single application in twenty-four hours quite suffices. Preliminary application of caustics, such as